Organometallic Compounds
Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 250 MG
NH-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group, and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Peg-based protac linker
- Used in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Capable of strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG3-acid) | 2055042-61-8 | 97.0% | C31H60N2O15 | 25 MG
N-(Boc-PEG3)-N-bis(PEG3-acid) is a PEG-based PROTAC linker. It is designed for use in the synthesis of PROTACs. This product is for research use only.
- PEG-based PROTAC linker
- For use in the synthesis of PROTACs
- For research use only
TARGETMOL CHEMICALS INC PLATYCODIN D 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Platycodin D may stimulate TNF-(alpha) synthesis or inhibit degradation of TNF-(alpha) mRNA. Platycodin D (10/30 uM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA). Platycodin D and D3 are useful as expectorant agents in the treatment of various airway diseases they can increase mucin release from rat and hamster tracheal surface epithelial cell culture and also from intact rat trachea upon nebulization. purity: 99%
Medchemexpress LLC Methyl-PEG3-bromide 10g
Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) | 2112737-19-4 | > 96% | C38H76N2O16 | 100 MG
N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting a specific protein. These molecules function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and not sold to patients.
- Peg-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC (S)-S007-1558 (GPVI antagonist 1) | 1327156-14-8 | 99.78% | C19H19N3O4S | 25 MG
(S)-S007-1558 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. It inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM.
- Glycoprotein VI (GPVI) platelet receptor antagonist
- Inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM
Medchemexpress LLC M-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 5 G
m-PEG5-Br is a PEG-based PROTAC linker. It is for research use only and not for sale to patients. This linker can be used in the synthesis of PROTACs, which consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC S -2- 2- tert-Buto 250mg
(S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid (Boc-his(trt)-aib-ohol) is a drug intermediate for synthesis of various active compounds
Medchemexpress LLC O,O'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[hydroxylamine] | 98627-70-4 | 98.0% | C8H20N2O5 | 100 MG
This product, Bis-aminooxy-PEG3, is a PEG-based PROTAC linker. It has a molecular weight of 224.25 and appears as a colorless to light yellow liquid.
- Consistent with structure based on ¹H NMR spectrum
- Consistent with structure based on MS